Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person The complex of HCFC1 and MLL1 is recruited to E2F1 target promoters

Class:Id	Reaction:9821269
_displayName	The complex of HCFC1 and MLL1 is recruited to E2F1 target promoters
_doRelease	FALSE
_timestamp	2022-12-01 15:12:30
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9821265] Orlic-Milacic, Marija, 2022-11-30
input	[Complex:9821263] MLL1 complex:HCFC1 [nucleoplasm] [Homo sapiens] [CandidateSet:9821279] E2F1:TFDP1,TFDP2:CCNA1 gene,E2F1 gene,RBL1 gene,(CDC25A gene) chromatin [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9821266] E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases [LiteratureReference:9821261] E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases
modified	[InstanceEdit:9821316] Orlic-Milacic, Marija, 2022-12-01 [InstanceEdit:9821353] Orlic-Milacic, Marija, 2022-12-01
name	The complex of HCFC1 and MLL1 is recruited to E2F1 target promoters
output	[CandidateSet:9821296] MLL1 complex:HCFC1:E2F1:TFDP1,TFDP2:CCNA1 gene chromatin,E2F1 gene chromatin,RBL1 gene chromatin,(CDC25A gene chromatin) [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9821235] HCFC1, HCFC2 bind the MLL1:MEN1 complex [Homo sapiens] [Reaction:9818937] MEN1 binds MLL1 complex [Homo sapiens] [Reaction:9675026] Formation of the MLL1 complex [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9821274] R-HSA-9821269.1
summation	[Summation:9821343] HCFC1 (also known as HCF1 or Host cell factor 1) directly bi...
(hasEvent)	[Pathway:9818561] Epigenetic regulation of gene expression by MLL1 complex [Homo sapiens]
(precedingEvent)	[Reaction:9821277] MLL1 complex trimethylates nucleosomes at promoters of E2F1 target genes [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by The complex of HCFC1 and MLL1 is recruited to E2F1 target promoters (9821269)