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Details on Person Ago2:Zfp277 endosiRNA hydrolyzes Zfp277 mRNA

Class:IdReaction:9820863
_displayNameAgo2:Zfp277 endosiRNA hydrolyzes Zfp277 mRNA
_doReleaseTRUE
_timestamp2023-08-08 17:53:19
authored[InstanceEdit:9820831] May, Bruce, 2022-11-20
catalystActivity[CatalystActivity:9820870] endoribonuclease activity, cleaving siRNA-paired mRNA of Ago2:Zfp277 endosiRNA [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9820878] May, Bruce, 2022-11-21
edited[InstanceEdit:9820831] May, Bruce, 2022-11-20
input[EntityWithAccessionedSequence:9820854] Zfp277 mRNA [cytosol] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9820897] Argonaute 2 is a key regulator of maternal mRNA degradation in mouse early embryos
modified[InstanceEdit:9841067] May, Bruce, 2023-08-08
nameAgo2:Zfp277 endosiRNA hydrolyzes Zfp277 mRNA
output[EntityWithAccessionedSequence:9820892] Zfp277 mRNA 3' fragment [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9820861] Zfp277 mRNA 5' fragment [cytosol] [Mus musculus]
releaseDate2023-09-13
reviewed[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9820918] R-MMU-9820863.1
summation[Summation:9820881] Before and during zygotic genome activation, Ago2 bound to a...
(inferredFrom)[Reaction:9820842] AGO2:endosiRNA hydrolyzes maternal mRNA in the zygote [Homo sapiens]
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No pathways have been reviewed or authored by Ago2:Zfp277 endosiRNA hydrolyzes Zfp277 mRNA (9820863)