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Details on Person Shamovsky, Veronica, 2022-11-07
| Class:Id | InstanceEdit:9820396 |
| _displayName | Shamovsky, Veronica, 2022-11-07 |
| _timestamp | 2022-11-07 22:13:15 |
| author | [Person:429259] Shamovsky, Veronica |
| dateTime | 2022-11-07 22:12:28 |
| (created) | [Person:9820377] Horne, Christopher R [RegulationReference:9820378] Negative regulation by 'TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane]' Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential [Person:9820379] Ma, Suchen [Person:9820380] Jiang, Zhaodi [Person:9820381] Zhang, Zhiyuan [InstanceEdit:9820382] Murphy, James M, 2022-11-07 [NegativeRegulation:9820383] Negative regulation by 'TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane]' [RegulationReference:9820384] Negative regulation by 'TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane]' CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling [NegativeRegulation:9820385] Negative regulation by 'K63polyUb-CFLAR(1-480) [cytosol]' [NegativeRegulation:9820386] Negative regulation by 'TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane]' |
| (modified) | [Reaction:83582] TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 [Homo sapiens] [Reaction:3371360] FLIP(L) and procaspase-8 form heterodimer in TNF signaling [Homo sapiens] [Reaction:5357776] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG [Homo sapiens] [Pathway:5357905] Regulation of TNFR1 signaling [Homo sapiens] [Summation:9793440] Under basal conditions, mixed lineage kinase domain-like pro... [BlackBoxEvent:9793444] ITCH polyubiquitinates MLKL at K50 [Homo sapiens] [Summation:9793449] Exogenous stimuli provoke assembly of the receptor-interacti... [Reaction:9793451] MLKL binds ITCH [Homo sapiens] [Reaction:9793472] RIPK3 binds p-S9-PRKN [Homo sapiens] [BlackBoxEvent:9793485] PRKN polyubiquitinates RIPK3 [Homo sapiens] |
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No pathways have been reviewed or authored by Shamovsky, Veronica, 2022-11-07 (9820396)