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Details on Person MLL1 complex bound to MEN1 and PSIP1 trimethylates nucleosomes at target gene promotres

Class:Id	Reaction:9819144
_displayName	MLL1 complex bound to MEN1 and PSIP1 trimethylates nucleosomes at target gene promotres
_doRelease	FALSE
_timestamp	2022-11-01 17:50:37
catalystActivity	[CatalystActivity:9819151] histone H3K4 methyltransferase activity of MLL1 complex:MEN1:PSIP1:Target genes chromatin [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9819146] Orlic-Milacic, Marija, 2022-11-01
input	[Complex:9818985] MLL1 complex:MEN1:PSIP1:Target genes chromatin [nucleoplasm] [Homo sapiens] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm]
isChimeric	FALSE
name	MLL1 complex bound to MEN1 and PSIP1 trimethylates nucleosomes at target gene promotres
output	[Complex:9819142] MLL1 complex:MEN1:PSIP1:target genes H3K4me3 chromatin [nucleoplasm] [Homo sapiens] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm]
precedingEvent	[Reaction:9818984] The complex of MLL1, MEN1 and PSIP1 binds target gene loci [Homo sapiens] [Reaction:9818954] PSIP1 binds MLL1 and MEN1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9819155] R-HSA-9819144.1
(hasEvent)	[Pathway:9818561] Epigenetic regulation of gene expression by MLL1 complex [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9819149] Expression of MLL1 target genes is positively regulated by MLL1, MEN1 and PSIP1 [Homo sapiens]
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No pathways have been reviewed or authored by MLL1 complex bound to MEN1 and PSIP1 trimethylates nucleosomes at target gene promotres (9819144)