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Details on Person ULK1 phosphorylates RIPK1 at S357

Class:Id	Reaction:9819106
_displayName	ULK1 phosphorylates RIPK1 at S357
_doRelease	TRUE
_timestamp	2022-11-01 22:04:54
authored	[InstanceEdit:9818960] Shamovsky, Veronica, 2022-10-31
catalystActivity	[CatalystActivity:9819103] protein serine/threonine kinase activity of ULK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9819085] protein serine/threonine kinase activity of ULK1 [cytosol] The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9819079] Shamovsky, Veronica, 2022-11-01
edited	[InstanceEdit:9818840] Shamovsky, Veronica, 2022-10-24
input	[Complex:140935] TRAF2:TRADD:RIPK1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9819092] The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
modified	[InstanceEdit:9819164] Shamovsky, Veronica, 2022-11-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ULK1 phosphorylates RIPK1 at S357
output	[Complex:9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:83582] TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 [Homo sapiens] [Reaction:83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 [Homo sapiens]
releaseDate	2022-12-07
reviewed	[InstanceEdit:9818965] Tu, Hailin, 2022-10-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9819120] R-HSA-9819106.2
summation	[Summation:9819084] Autophagy controls programmed cell death through different c...
(hasEvent)	[Pathway:5357905] Regulation of TNFR1 signaling [Homo sapiens]
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No pathways have been reviewed or authored by ULK1 phosphorylates RIPK1 at S357 (9819106)