Reactome: A Curated Pathway Database
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Details on Person In wild type mouse embryonic fibroblasts (MEFs) the two clea...

Class:IdSummation:9818641
_displayNameIn wild type mouse embryonic fibroblasts (MEFs) the two clea...
_timestamp2023-02-10 17:41:30
created[InstanceEdit:9818636] Orlic-Milacic, Marija, 2022-10-19
modified[InstanceEdit:9828125] Orlic-Milacic, Marija, 2023-02-10
textIn wild type mouse embryonic fibroblasts (MEFs) the two cleavage fragments of Kmt2b (Mll2) predicted based on the sequence conservation with Kmt2a (also known as Mll or Mll1) are detected. The cleavage does not occur in Tasp1 null MEFs and is rescued upon exogenous expression of recombinant Tasp1 (Takeda et al. 2006).
(summation)[Reaction:9818635] Tasp1 cleaves Kmt2b [Mus musculus]
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No pathways have been reviewed or authored by In wild type mouse embryonic fibroblasts (MEFs) the two clea... (9818641)