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Details on Person Expression of ZSCAN4 in the embryo

Class:Id	BlackBoxEvent:9818523
_displayName	Expression of ZSCAN4 in the embryo
_doRelease	TRUE
_timestamp	2023-08-08 17:58:33
authored	[InstanceEdit:9818493] May, Bruce, 2022-10-17
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9818488] May, Bruce, 2022-10-18
edited	[InstanceEdit:9818493] May, Bruce, 2022-10-17
inferredFrom	[BlackBoxEvent:9820700] Expression of Zscan4 in the embryo [Mus musculus]
input	[EntityWithAccessionedSequence:9816413] ZSCAN4 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9818480] Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation [LiteratureReference:9816444] Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons [LiteratureReference:9820754] Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos [LiteratureReference:9820756] Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
modified	[InstanceEdit:9820789] May, Bruce, 2022-11-19 [InstanceEdit:9823275] May, Bruce, 2023-01-05 [InstanceEdit:9841067] May, Bruce, 2023-08-08
name	Expression of ZSCAN4 in the embryo
output	[EntityWithAccessionedSequence:9816447] ZSCAN4 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9816396] DUX4, TPRXL, TPRX1, TPRX2, EP300, and CREBBP bind the ZSCAN4 gene [Homo sapiens] [BlackBoxEvent:9816369] Expression of DUX4 in the zygote [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9818502] Positive gene expression regulation by 'DUX4:TPRXL:TPRX1:TPRX2:EP300:CREBBP:ZSCAN4 gene [nucleoplasm]'
regulationReference	[RegulationReference:9820715] Positive gene expression regulation by 'DUX4:TPRXL:TPRX1:TPRX2:EP300:CREBBP:ZSCAN4 gene [nucleoplasm]' Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons
releaseDate	2023-09-13
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9818551] R-HSA-9818523.1
summation	[Summation:9820744] The ZSCAN4 gene, the single human homolog of the Zscan4 gene...
(hasEvent)	[Pathway:9819196] Zygotic genome activation (ZGA) [Homo sapiens]
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No pathways have been reviewed or authored by Expression of ZSCAN4 in the embryo (9818523)