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Details on Person May, Bruce, 2022-10-08
| Class:Id | InstanceEdit:9818020 |
| _displayName | May, Bruce, 2022-10-08 |
| _timestamp | 2022-10-08 12:18:29 |
| author | [Person:203835] May, Bruce |
| dateTime | 2022-10-08 12:16:37 |
| (modified) | [Summation:389138] Colony-stimulating factor 1 receptor (CSF1R, CSF-1R) is a pr... [Complex:389153] CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] [Homo sapiens] [Reaction:389156] CSF1 dimer binds CSF1R or IL34 [Homo sapiens] [Pathway:9680350] Signaling by CSF1 (M-CSF) in myeloid cells [Homo sapiens] [CatalystActivity:9680390] guanyl-nucleotide exchange factor activity of CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane] [Complex:9680629] Csf1 dimer:PolyUb,p-8Y-Csf1r dimer:Fyn,Hck,Src,Yes1:p-Y-Cbl [plasma membrane] [Mus musculus] [BlackBoxEvent:9680646] Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated [Mus musculus] [Complex:9680664] Csf1 dimer:PolyUb,p-8Y-Csf1r dimer:Fyn,Hck,Src,Yes1:p-Y-Gab2:p-Y-Gab3:Grap2:Inpp5d:Inppl1:Pi3k:Ptpn11:p-Y-Shc1:p-Y-Plcg2 [plasma membrane] [Mus musculus] [Summation:9680761] After the Csf1 dimer binds a Csfr1 monomer, a second molecul... [Summation:9681118] After the CSF1 dimer or IL34 dimer binds a CSF1R monomer, a ... |
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No pathways have been reviewed or authored by May, Bruce, 2022-10-08 (9818020)