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Details on Person 3'-5'-DNA exonuclease activity of MRN:CtIP [nucleoplasm]

Class:IdCatalystActivity:981788
_displayName3'-5'-DNA exonuclease activity of MRN:CtIP [nucleoplasm]
_timestamp2024-05-14 19:03:12
activeUnit[EntityWithAccessionedSequence:59544] MRE11A [nucleoplasm] [Homo sapiens]
activity[GO_MolecularFunction:23750] 3'-5'-DNA exonuclease activity
created[InstanceEdit:981786] May, B, 2010-10-27
modified[InstanceEdit:5255525] May, B, 2014-02-06
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
physicalEntity[Complex:981776] MRN:CtIP [nucleoplasm] [Homo sapiens]
(catalystActivity)[BlackBoxEvent:9023943] MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end [Homo sapiens]
[CatalystActivityReference:9643714] 3'-5'-exodeoxyribonuclease activity of MRN:CtIP [nucleoplasm] The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
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No pathways have been reviewed or authored by 3'-5'-DNA exonuclease activity of MRN:CtIP [nucleoplasm] (981788)
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