Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Btg4 binds Cnot7 of the CCR4-NOT complex, Pabpn1l, and eIF4E of the mRNP

Class:IdReaction:9817704
_displayNameBtg4 binds Cnot7 of the CCR4-NOT complex, Pabpn1l, and eIF4E of the mRNP
_doReleaseTRUE
_timestamp2023-08-08 17:53:43
authored[InstanceEdit:9817540] May, Bruce, 2022-09-23
compartment[Compartment:70101] cytosol
created[InstanceEdit:9817627] May, Bruce, 2022-09-26
edited[InstanceEdit:9817540] May, Bruce, 2022-09-23
input[EntityWithAccessionedSequence:9817679] Btg4 [cytosol] [Mus musculus]
[Complex:9817653] CCR4-NOT complex (Cnot7) [cytosol] [Mus musculus]
[Complex:9817660] mRNP regulated by Btg4 [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9820794] Pabpn1l [cytosol] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9817712] BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes
[LiteratureReference:9819212] The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs
[LiteratureReference:9819228] BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis
[LiteratureReference:9820818] PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal-to-zygotic transition
modified[InstanceEdit:9819298] May, Bruce, 2022-11-02
[InstanceEdit:9820831] May, Bruce, 2022-11-20
[InstanceEdit:9820934] May, Bruce, 2022-11-21
[InstanceEdit:9822429] May, Bruce, 2022-12-23
[InstanceEdit:9841067] May, Bruce, 2023-08-08
nameBtg4 binds Cnot7 of the CCR4-NOT complex, Pabpn1l, and eIF4E of the mRNP
output[Complex:9817642] CCR4-NOT:Btg4:Pabpn1l:mRNP [cytosol] [Mus musculus]
releaseDate2023-09-13
reviewed[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9817740] R-MMU-9817704.1
summation[Summation:9819232] Btg4 binds eIF4E of the mRNA-protein complex (mRNP) and Cnot...
(inferredFrom)[Reaction:9817692] BTG4 binds CNOT7 of the CCR4-NOT complex, PABPN1L, and eIF4E of the mRNP [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Btg4 binds Cnot7 of the CCR4-NOT complex, Pabpn1l, and eIF4E of the mRNP (9817704)