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Details on Person DUX4 binds HSATII pericentric repeats (Young et al. 2013, He...
| Class:Id | Summation:9817440 |
|---|---|
| _displayName | DUX4 binds HSATII pericentric repeats (Young et al. 2013, He... |
| _timestamp | 2022-12-10 11:46:29 |
| created | [InstanceEdit:9817437] May, Bruce, 2022-09-18 |
| literatureReference | [LiteratureReference:9817433] A strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development |
| modified | [InstanceEdit:9820789] May, Bruce, 2022-11-19 [InstanceEdit:9821723] May, Bruce, 2022-12-10 |
| text | DUX4 binds HSATII pericentric repeats (Young et al. 2013, Hendrickson et al. 2017). Binding of DUX4 causes transcription of pericentric satellites (Young et al. 2013, Hendrickson et al. 2017) which is bidirectional (Shadle et al. 2019). In mouse, transcription of pericentric satellites is required for formation of chromocenters (conglomerations of heterochromatin containing centromeres of multiple chromosomes) and subsequent development (Probst et al. 2010). |
| (summation) | [Reaction:9817254] DUX4 binds HSATII pericentric repeat [Homo sapiens] |
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No pathways have been reviewed or authored by DUX4 binds HSATII pericentric repeats (Young et al. 2013, He... (9817440)
