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Details on Person Expression of Dux in the embryo

Class:IdBlackBoxEvent:9816403
_displayNameExpression of Dux in the embryo
_doReleaseTRUE
_timestamp2023-08-08 17:57:39
authored[InstanceEdit:9816375] May, Bruce, 2022-09-07
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9816422] May, Bruce, 2022-09-12
edited[InstanceEdit:9816375] May, Bruce, 2022-09-07
input[EntityWithAccessionedSequence:9816365] Dux gene [nucleoplasm] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9816434] DPPA2 and DPPA4 are necessary to establish a 2C-like state in mouse embryonic stem cells
[LiteratureReference:9816450] Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program
[LiteratureReference:9816397] Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region
[LiteratureReference:9816364] p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models
modified[InstanceEdit:9817324] May, Bruce, 2022-09-15
[InstanceEdit:9817766] May, Bruce, 2022-09-26
[InstanceEdit:9820934] May, Bruce, 2022-11-21
[InstanceEdit:9823275] May, Bruce, 2023-01-05
[InstanceEdit:9841067] May, Bruce, 2023-08-08
nameExpression of Dux in the embryo
output[EntityWithAccessionedSequence:9816370] Dux [nucleoplasm] [Mus musculus]
regulatedBy[PositiveGeneExpressionRegulation:9816423] Positive gene expression regulation by 'Dppa2:Dppa4:p-S18-Tp53:Dux gene [nucleoplasm]'
releaseDate2023-09-13
reviewed[InstanceEdit:9841065] Xie, Wei, 2023-08-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9816464] R-MMU-9816403.1
summation[Summation:9820852] Dux is expressed during the initial, minor wave of zygotic g...
(inferredFrom)[BlackBoxEvent:9816369] Expression of DUX4 in the zygote [Homo sapiens]
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