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Details on Person CTBP1 (Cowger et al. 2007, Bruton et al. 2008; Deng et al. 2...

Class:IdSummation:9816020
_displayNameCTBP1 (Cowger et al. 2007, Bruton et al. 2008; Deng et al. 2...
_timestamp2025-05-28 22:09:45
created[InstanceEdit:9816025] Orlic-Milacic, Marija, 2022-08-31
literatureReference[LiteratureReference:9768255] Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3
[LiteratureReference:996734] Coordinated histone modifications mediated by a CtBP co-repressor complex
[LiteratureReference:9768534] Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2
[LiteratureReference:9931136] Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence
[LiteratureReference:9931739] PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions
[LiteratureReference:9931747] Ataxin-1 occupies the promoter region of E-cadherin in vivo and activates CtBP2-repressed promoter
[LiteratureReference:9931744] Transcriptional down-regulation of Brca1 and E-cadherin by CtBP1 in breast cancer
[LiteratureReference:9765962] MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP
[LiteratureReference:9931732] BBOX1-AS1 promotes gastric cardia adenocarcinoma progression via interaction with CtBP2 to facilitate the epithelial-mesenchymal transition process
modified[InstanceEdit:9931752] Orlic-Milacic, Marija, 2024-12-12
[InstanceEdit:9931753] Orlic-Milacic, Marija, 2024-12-12
[InstanceEdit:9936173] Orlic-Milacic, Marija, 2025-01-21
[InstanceEdit:9953204] Orlic-Milacic, Marija, 2025-05-28
textCTBP1 (Cowger et al. 2007, Bruton et al. 2008; Deng et al. 2012) and CTBP2 (Zhao et al. 2007; Lee et al. 2011), known to function as homo- or heterodimers (Shi et al. 2003), bind to the CDH1 gene promoter, likely in association with other transcription factors, such as ZEB1 (Shi et al. 2003; Ichikawa et al. 2015; Zou et al. 2024) or ZNF217 (Cowger et al. 2007; Bruton et al. 2008).
(summation)[Reaction:9768477] CTBP1,CTBP2 binds CDH1 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by CTBP1 (Cowger et al. 2007, Bruton et al. 2008; Deng et al. 2... (9816020)
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