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Details on Person ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position

Class:IdReaction:981497
_displayNameST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position
_doReleaseTRUE
_timestamp2025-04-08 08:43:46
authored[InstanceEdit:977066] Jassal, B, 2010-10-15
catalystActivity[CatalystActivity:981487] beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase activity of ST3GAL1-4 [Golgi membrane]
compartment[Compartment:20699] Golgi membrane
[Compartment:17963] Golgi lumen
created[InstanceEdit:981495] Jassal, B, 2010-10-21
crossReference[DatabaseIdentifier:9942409] RHEA:21617
edited[InstanceEdit:977066] Jassal, B, 2010-10-15
input[DefinedSet:1462240] Core 1 mucins [Golgi lumen] [Homo sapiens]
[SimpleEntity:727815] CMP-Neu5Ac [Golgi lumen]
isChimericFALSE
literatureReference[LiteratureReference:981484] Molecular cloning and expression of Galbeta1,3GalNAc alpha2, 3-sialyltransferase from human fetal liver
[LiteratureReference:981493] Molecular cloning and expression of human Gal beta 1,3GalNAc alpha 2,3-sialytransferase (hST3Gal II)
[LiteratureReference:981485] Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase
[LiteratureReference:981483] Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line
modified[InstanceEdit:981810] Jassal, B, 2010-10-27
[InstanceEdit:981828] Jassal, B, 2010-10-27
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1462326] Wu, G, 2011-07-28
[InstanceEdit:1463492] Jassal, B, 2011-07-28
[InstanceEdit:1963546] Jassal, B, 2011-11-03
[InstanceEdit:1963553] Jassal, B, 2011-11-03
[InstanceEdit:1964511] Jassal, B, 2011-11-04
[InstanceEdit:1965758] Jassal, B, 2011-11-04
[InstanceEdit:4088185] Jassal, Bijay, 2013-08-12
[InstanceEdit:9756078] Jassal, Bijay, 2021-10-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9942394] Stephan, Ralf, 2025-03-16
[InstanceEdit:9942597] Stephan, Ralf, 2025-03-18
[InstanceEdit:9944934] Stephan, Ralf, 2025-04-08
nameST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position
output[SimpleEntity:727810] CMP [Golgi lumen]
[DefinedSet:1463569] Sialyl-2,3 T antigens [Golgi lumen] [Homo sapiens]
[SimpleEntity:425969] H+ [Golgi lumen]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2011-12-06
reviewed[InstanceEdit:1964508] Ferrer, A, 2011-11-04
[InstanceEdit:9944933] D'Eustachio, Peter, 2025-04-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016604] R-HSA-981497.4
structureModified[InstanceEdit:9942394] Stephan, Ralf, 2025-03-16
summation[Summation:981494] The human genes ST3GAL1-4 encode for sialyltransferases1-4 r...
(hasEvent)[Pathway:977068] Termination of O-glycan biosynthesis [Homo sapiens]
(precedingEvent)[Reaction:981809] ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787223] Update Tracker - [Reaction:981497] ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position - v46:[modifyText]
[_UpdateTracker:9953625] Update Tracker - [Reaction:981497] ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position - v93:[removeOutput]
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