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Details on Person Expression of Foxa2 in the anterior primitive streak
Class:Id BlackBoxEvent:9796221
_displayName Expression of Foxa2 in the anterior primitive streak
_doRelease TRUE
_timestamp 2022-10-15 12:59:40
authored [InstanceEdit:9796305] May, Bruce, 2022-08-08
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9796202] May, Bruce, 2022-08-09
edited [InstanceEdit:9796305] May, Bruce, 2022-08-08
input [EntityWithAccessionedSequence:9796265] Foxa2 gene [nucleoplasm] [Mus musculus]
isChimeric FALSE
literatureReference [LiteratureReference:9796281] Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor [LiteratureReference:9796237] The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse [LiteratureReference:9796220] FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse [LiteratureReference:9796259] Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival [LiteratureReference:9796245] The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins [LiteratureReference:9796254] Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate [LiteratureReference:9796244] Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm [LiteratureReference:9796255] Identification of essential sequence motifs in the node/notochord enhancer of Foxa2 (Hnf3beta) gene that are conserved across vertebrate species [LiteratureReference:9796218] Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements [LiteratureReference:9815759] Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues [LiteratureReference:9818405] Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo [LiteratureReference:9815790] HNF-3 beta is essential for node and notochord formation in mouse development
modified [InstanceEdit:9815826] May, Bruce, 2022-08-27 [InstanceEdit:9818410] May, Bruce, 2022-10-15 [InstanceEdit:9818413] May, Bruce, 2022-10-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Expression of Foxa2 in the anterior primitive streak
output [EntityWithAccessionedSequence:187321] Foxa2 [nucleoplasm] [Mus musculus]
regulatedBy [PositiveGeneExpressionRegulation:9796196] Positive gene expression regulation by 'Tead2,Tead4:Yap1:Tbxt:Foxa2 gene [nucleoplasm]'
regulationReference [RegulationReference:9796197] Positive gene expression regulation by 'Tead2,Tead4:Yap1:Foxa2 gene [nucleoplasm]' Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor
releaseDate 2022-12-07
reviewed [InstanceEdit:9818412] Sasaki, Hiroshi, 2022-10-15
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48892] Mus musculus
stableIdentifier [StableIdentifier:9796330] R-MMU-9796221.2
summation [Summation:9796307] Foxa2 is first expressed at the anterior end of the primitiv...
(inferredFrom) [BlackBoxEvent:9796209] Expression of FOXA2 in the anterior primitive streak [Homo sapiens]
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