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Details on Person NFE2L2 dependent TXN expression

Class:IdBlackBoxEvent:9796045
_displayNameNFE2L2 dependent TXN expression
_doReleaseTRUE
_timestamp2023-08-21 16:36:18
authored[InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9796052] Tiwari, Krishna, 2022-08-04
edited[InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
input[EntityWithAccessionedSequence:9795738] Thioredoxin gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9841061] Rothfels, Karen, 2023-08-08
isChimericFALSE
literatureReference[LiteratureReference:9795431] Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice
[LiteratureReference:9795378] Regulation of the human thioredoxin gene promoter and its key substrates: a study of functional and putative regulatory elements
modified[InstanceEdit:9817832] Tiwari, Krishna, 2022-09-27
[InstanceEdit:9817933] Tiwari, Krishna, 2022-09-30
[InstanceEdit:9818736] Tiwari, Krishna, 2022-10-20
[InstanceEdit:9820604] Matthews, Lisa, 2022-11-13
[InstanceEdit:9841062] Tiwari, Krishna, 2023-08-08
[InstanceEdit:9842189] Matthews, Lisa, 2023-08-21
nameNFE2L2 dependent TXN expression
output[EntityWithAccessionedSequence:66000] TXN [cytosol] [Homo sapiens]
regulatedBy[PositiveGeneExpressionRegulation:9795945] Positive gene expression regulation by 'TXN gene:p-AcK-NFE2L2:CREBBP,EP300:MAFK [nucleoplasm]'
regulationReference[RegulationReference:9795939] Positive gene expression regulation by 'TXN gene:p-AcK-NFE2L2:CREBBP,EP300:MAFK [nucleoplasm]' Regulation of the human thioredoxin gene promoter and its key substrates: a study of functional and putative regulatory elements
releaseDate2023-09-13
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9796100] R-HSA-9796045.1
summation[Summation:9818701] NFE2L2 regulates the expression of TXN (Thioredoxin) by bind...
(hasEvent)[Pathway:9796073] Krishna: NRF2-KEAP1 pathway [Homo sapiens]
[Pathway:9818027] NFE2L2 regulating anti-oxidant/detoxification enzymes [Homo sapiens]
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No pathways have been reviewed or authored by NFE2L2 dependent TXN expression (9796045)