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Details on Person NFE2L2 dependent TXN expression
Class:Id BlackBoxEvent:9796045
_displayName NFE2L2 dependent TXN expression
_doRelease TRUE
_timestamp 2023-08-21 16:36:18
authored [InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9796052] Tiwari, Krishna, 2022-08-04
edited [InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
input [EntityWithAccessionedSequence:9795738] Thioredoxin gene [nucleoplasm] [Homo sapiens]
internalReviewed [InstanceEdit:9841061] Rothfels, Karen, 2023-08-08
isChimeric FALSE
literatureReference [LiteratureReference:9795431] Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice [LiteratureReference:9795378] Regulation of the human thioredoxin gene promoter and its key substrates: a study of functional and putative regulatory elements
modified [InstanceEdit:9817832] Tiwari, Krishna, 2022-09-27 [InstanceEdit:9817933] Tiwari, Krishna, 2022-09-30 [InstanceEdit:9818736] Tiwari, Krishna, 2022-10-20 [InstanceEdit:9820604] Matthews, Lisa, 2022-11-13 [InstanceEdit:9841062] Tiwari, Krishna, 2023-08-08 [InstanceEdit:9842189] Matthews, Lisa, 2023-08-21
name NFE2L2 dependent TXN expression
output [EntityWithAccessionedSequence:66000] TXN [cytosol] [Homo sapiens]
regulatedBy [PositiveGeneExpressionRegulation:9795945] Positive gene expression regulation by 'TXN gene:p-AcK-NFE2L2:CREBBP,EP300:MAFK [nucleoplasm]'
regulationReference [RegulationReference:9795939] Positive gene expression regulation by 'TXN gene:p-AcK-NFE2L2:CREBBP,EP300:MAFK [nucleoplasm]' Regulation of the human thioredoxin gene promoter and its key substrates: a study of functional and putative regulatory elements
releaseDate 2023-09-13
reviewStatus [ReviewStatus:9821383] three stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9796100] R-HSA-9796045.1
summation [Summation:9818701] NFE2L2 regulates the expression of TXN (Thioredoxin) by bind...
(hasEvent) [Pathway:9796073] Krishna: NRF2-KEAP1 pathway [Homo sapiens] [Pathway:9818027] NFE2L2 regulating anti-oxidant/detoxification enzymes [Homo sapiens]
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No pathways have been reviewed or authored by NFE2L2 dependent TXN expression (9796045)