Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Oxociprofloxacin (oxo-Cipro), as the major ciprofloxacin met...
| Class:Id | Summation:9795156 |
|---|---|
| _displayName | Oxociprofloxacin (oxo-Cipro), as the major ciprofloxacin met... |
| _timestamp | 2022-09-25 14:51:43 |
| created | [InstanceEdit:9795152] Stephan, Ralf, 2022-07-29 |
| modified | [InstanceEdit:9817609] Stephan, Ralf, 2022-09-25 |
| text | Oxociprofloxacin (oxo-Cipro), as the major ciprofloxacin metabolite in urine, is transported by an unknown active transporter from the cytosol of primary hepatocytes back to extracellular space of the blood vessels (reviewed by Sörgel, 1989). There are two active transporters highly expressed in the basolateral membranes of hepatocytes: ATP-binding cassette sub-family C members 3 and 4 (ABCC3, ABCC4) (reviewed by Jetter & Kullack-Ublick, 2019). It is possible that ABCC3 and/or ABCC4 are responsible for excretion of oxo-Cipro into blood plasma. |
| (summation) | [BlackBoxEvent:9795153] Basolateral excretion of oxo-Cipro [Homo sapiens] |
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No pathways have been reviewed or authored by Oxociprofloxacin (oxo-Cipro), as the major ciprofloxacin met... (9795156)
