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Details on Person Charting Brachyury-mediated developmental pathways during early mouse embryogenesis

Class:IdLiteratureReference:9794956
_displayNameCharting Brachyury-mediated developmental pathways during early mouse embryogenesis
_timestamp2022-07-25 06:29:33
author[Person:9794970] Lolas, Macarena
[Person:9794957] Valenzuela, Pablo D T
[Person:9794966] Tjian, Robert
[Person:508053] Liu, Zhe
created[InstanceEdit:9794964] May, Bruce, 2022-07-25
journalProc Natl Acad Sci U S A
pages4478-83
pubMedIdentifier24616493
titleCharting Brachyury-mediated developmental pathways during early mouse embryogenesis
volume111
year2014
(literatureReference)[BlackBoxEvent:9754300] Expression of T (Tbxt) in the primitive streak [Mus musculus]
[Reaction:9796226] Tead2,Tead4:Yap1 and Tbxt bind the Foxa2 gene [Mus musculus]
[Pathway:9796292] Formation of axial mesoderm [Homo sapiens]
[Reaction:9823738] Tcf7l2:Ctnnb1, Foxa2, Mixl1, and Gata4 bind the Sox17 gene [Mus musculus]
[BlackBoxEvent:9823745] Expression of Sox17 in definitive endoderm [Mus musculus]
[Reaction:9824464] Tbxt (Brachyury) binds the Foxa2 gene [Mus musculus]
[BlackBoxEvent:9825053] Expression of Foxa2 in the definitive endoderm [Mus musculus]
[RegulationReference:9793399] Positive gene expression regulation by 'Tbxt [nucleoplasm]' Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation
[RegulationReference:9823862] Positive gene expression regulation by 'Tcf7l2:Ctnnb1:Foxa2:Tbxt:Gata4:Sox17 gene [nucleoplasm]' Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse
[RegulationReference:9825321] Positive gene expression regulation by 'Tbxt:Foxa2 gene [nucleoplasm]' Charting Brachyury-mediated developmental pathways during early mouse embryogenesis
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