Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person endopeptidase activity of IDE, CTSD [endosome lumen] Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

Class:Id	CatalystActivityReference:9794497
_displayName	endopeptidase activity of IDE, CTSD [endosome lumen] Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
_timestamp	2022-08-31 21:29:09
catalystActivity	[CatalystActivity:74729] endopeptidase activity of IDE, CTSD [endosome lumen]
created	[InstanceEdit:9794499] D'Eustachio, Peter, 2022-07-12
literatureReference	[LiteratureReference:9794501] Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme [LiteratureReference:9794498] Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme [LiteratureReference:9816120] Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme [LiteratureReference:9816121] Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D [LiteratureReference:9816131] Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism
modified	[InstanceEdit:9794517] D'Eustachio, Peter, 2022-07-12 [InstanceEdit:9816122] D'Eustachio, Peter, 2022-08-31
(catalystActivityReference)	[BlackBoxEvent:74730] Insulin degradation [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by endopeptidase activity of IDE, CTSD [endosome lumen] Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme (9794497)