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Details on Person Expression of Mesp2 in presomitic mesoderm

Class:Id	BlackBoxEvent:9793928
_displayName	Expression of Mesp2 in presomitic mesoderm
_doRelease	TRUE
_timestamp	2023-05-10 01:57:39
authored	[InstanceEdit:9793929] May, Bruce, 2022-06-19
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9793807] May, Bruce, 2022-06-24
edited	[InstanceEdit:9793929] May, Bruce, 2022-06-19
input	[EntityWithAccessionedSequence:9793860] Mesp2 gene [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9793841] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2 [LiteratureReference:9793863] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression [LiteratureReference:9793818] Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation [LiteratureReference:9793812] Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development [LiteratureReference:9794051] The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis [LiteratureReference:9794087] Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis
modified	[InstanceEdit:9794076] May, Bruce, 2022-06-27 [InstanceEdit:9819299] May, Bruce, 2022-11-02 [InstanceEdit:9820534] May, Bruce, 2022-11-09 [InstanceEdit:9825657] May, Bruce, 2023-01-26 [InstanceEdit:9827742] May, Bruce, 2023-02-01 [InstanceEdit:9827744] May, Bruce, 2023-02-02 [InstanceEdit:9828398] May, Bruce, 2023-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9834683] May, Bruce, 2023-05-10
name	Expression of Mesp2 in presomitic mesoderm
output	[EntityWithAccessionedSequence:9793922] Mesp2 [nucleoplasm] [Mus musculus]
regulatedBy	[PositiveGeneExpressionRegulation:9793861] Positive gene expression regulation by 'Tbx6:Mesp2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9793895] Positive gene expression regulation by 'Tbx6:Mesp2 gene [nucleoplasm]' Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2
releaseDate	2022-12-07
requiredInputComponent	[EntityWithAccessionedSequence:3927823] Foxc1 [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:3927958] Foxc2 [nucleoplasm] [Mus musculus]
reviewed	[InstanceEdit:9820530] Yamaguchi, Terry P, 2022-11-09 [InstanceEdit:9820524] Chalamalasetty, Ravindra B, 2022-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9793964] R-MMU-9793928.3
summation	[Summation:9794053] Mesp2 is expressed in the presomitic mesoderm (Saga et al. 1...
(inferredFrom)	[BlackBoxEvent:9793933] Expression of MESP2 in presomitic mesoderm [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9846714] Update Tracker - [BlackBoxEvent:9793928] Expression of Mesp2 in presomitic mesoderm - v84:[addLiteratureReference, modifyText]
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