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Details on Person TBX6 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:9793377
_displayName	TBX6 [nucleoplasm]
_timestamp	2022-06-12 15:38:43
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9793373] May, Bruce, 2022-06-12
endCoordinate	436
name	TBX6 T-box transcription factor TBX6 TBX6_HUMAN
referenceEntity	[ReferenceGeneProduct:65737] UniProt:O95947 TBX6 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9793396] R-HSA-9793377.1
startCoordinate	1
(activeUnit)	[PositiveGeneExpressionRegulation:9793803] Positive gene expression regulation by 'LEF1:CTNNB1:TBX6:DLL1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9793870] Positive gene expression regulation by 'TBX6:MESP2 gene [nucleoplasm]'
(hasComponent)	[Complex:9793386] CTNNB1:LEF1:TBX6:MSGN1 gene [nucleoplasm] [Homo sapiens] [Complex:9793846] LEF1:CTNNB1:TBX6:DLL1 gene [nucleoplasm] [Homo sapiens] [Complex:9793894] TBX6:MESP2 gene [nucleoplasm] [Homo sapiens] [Complex:9824263] LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] [Homo sapiens] [Complex:9824276] HES7:LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] [Homo sapiens] [Complex:9825558] TBX6:RIPPLY2:26S proteasome [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9793382] TBX6 and LEF1:CTNNB1 bind the MSGN1 gene [Homo sapiens] [Reaction:9793837] TBX6 binds the MESP2 gene [Homo sapiens] [Reaction:9793887] TBX6 and LEF1:CTNNB1 bind the DLL1 gene [Homo sapiens] [Reaction:9824266] LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm [Homo sapiens] [Reaction:9825555] RIPPLY2 binds TBX6 and recruits the 26S proteasome [Homo sapiens]
(output)	[BlackBoxEvent:9793383] Expression of TBX6 in paraxial mesoderm [Homo sapiens]
(regulator)	[NegativeGeneExpressionRegulation:9833051] Negative gene expression regulation by 'TBX6 [nucleoplasm]'
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No pathways have been reviewed or authored by TBX6 [nucleoplasm] (9793377)