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Details on Person AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5
| Class:Id | LiteratureReference:9792880 |
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| _displayName | AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5 |
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| _timestamp | 2022-05-31 18:43:22 |
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| author | [Person:195702] Zhao, W
[Person:9685181] Shi, Chong-Shan
[Person:9792851] Harrison, Kathleen
[Person:9686351] Hwang, Il-Young
[Person:9685241] Nabar, Neel R
[Person:5687970] Wang, Min
[Person:9685192] Kehrl, John H |
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| created | [InstanceEdit:9792844] Shamovsky, Veronica, 2022-05-31 |
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| journal | J Immunol |
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| pages | 2255-2264 |
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| pubMedIdentifier | 32929041 |
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| title | AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5 |
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| volume | 205 |
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| year | 2020 |
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| (literatureReference) | [Reaction:9792854] AKT phosphorylates NLRP3 at S5 [Homo sapiens]
[BlackBoxEvent:9792857] TRIM31 polyubiquitinates NLRP3 at K496 [Homo sapiens]
[Reaction:9792869] NLRP3 binds TRIM31 [Homo sapiens]
[RegulationReference:9792848] Negative regulation by 'p-S5-NLRP3 [cytosol]' AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5
[CatalystActivityReference:9792862] ubiquitin protein ligase activity of NLRP3:TRIM31:Ub:UBE2D1 [cytosol] AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5
[CatalystActivityReference:9792904] protein serine/threonine kinase activity of p-AKT1,p-AKT2 [plasma membrane] AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5
[Summation:9792871] Tripartite motif-containing protein 31 (TRIM31) negatively r...
[Summation:9792875] Phosphorylation of NLRP3 at S5 suppresses NLRP3 inflammasome...
[Summation:9792886] In vitro binding assay showed that tripartite motif containi... |
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No pathways have been reviewed or authored by AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5 (9792880)
