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Details on Person SLC9B2 exchanges Li+ for H+

Class:Id	Reaction:9774547
_displayName	SLC9B2 exchanges Li+ for H+
_doRelease	FALSE
_timestamp	2022-05-25 17:21:55
authored	[InstanceEdit:9774564] D'Eustachio, Peter, 2022-05-25
catalystActivity	[CatalystActivity:9774554] lithium:proton antiporter activity of SLC9B2 dimer [mitochondrial inner membrane]
catalystActivityReference	[CatalystActivityReference:9774556] lithium:proton antiporter activity of SLC9B2 dimer [mitochondrial inner membrane] Dissecting the proton transport pathway in electrogenic Na⁺/H⁺ antiporters
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:17927] mitochondrial intermembrane space [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9774550] D'Eustachio, Peter, 2022-05-25
edited	[InstanceEdit:9774564] D'Eustachio, Peter, 2022-05-25
input	[SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:2889057] Li+ [mitochondrial intermembrane space]
isChimeric	FALSE
literatureReference	[LiteratureReference:9774548] Characterization of the sodium/hydrogen exchanger NHA2 [LiteratureReference:9774568] Integrating mass spectrometry with MD simulations reveals the role of lipids in Na⁺/H⁺ antiporters [LiteratureReference:2889082] Proton-sodium stoichiometry of NhaA, an electrogenic antiporter from Escherichia coli [LiteratureReference:9774570] Dissecting the proton transport pathway in electrogenic Na⁺/H⁺ antiporters [LiteratureReference:2889065] A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension
modified	[InstanceEdit:9774578] D'Eustachio, Peter, 2022-05-25
name	SLC9B2 exchanges Li+ for H+ H(+)(in) + Li(+)(out) => H(+)(out) + Li(+)(in)
output	[SimpleEntity:163953] H+ [mitochondrial intermembrane space] [SimpleEntity:2889068] Li+ [mitochondrial matrix]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9774576] R-HSA-9774547.1
summation	[Summation:9774559] The widely expressed mitochondrial sodium/hydrogen exchanger...
(hasEvent)	[Pathway:2672351] Stimuli-sensing channels [Homo sapiens]
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No pathways have been reviewed or authored by SLC9B2 exchanges Li+ for H+ (9774547)