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Details on Person Histidine is decarboxylated to histamine

Class:IdReaction:977301
_displayNameHistidine is decarboxylated to histamine
_doReleaseTRUE
_timestamp2024-11-08 15:22:51
authored[InstanceEdit:977306] Stephan, R, 2010-10-15
catalystActivity[CatalystActivity:977296] histidine decarboxylase activity of PXLP-K305-HDC dimer [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:977299] Jassal, B, 2010-10-18
crossReference[DatabaseIdentifier:9925951] RHEA:20841
edited[InstanceEdit:977299] Jassal, B, 2010-10-18
goBiologicalProcess[GO_BiologicalProcess:654] histamine biosynthetic process
input[SimpleEntity:29612] L-His [cytosol]
[SimpleEntity:70106] H+ [cytosol]
internalReviewed[InstanceEdit:9926227] D'Eustachio, Peter, 2024-10-31
isChimericFALSE
literatureReference[LiteratureReference:977297] Functional analysis of alternatively spliced transcripts of the human histidine decarboxylase gene and its expression in human tissues and basophilic leukemia cells
modified[InstanceEdit:1828028] Jassal, B, 2011-10-26
[InstanceEdit:1877997] Jassal, Bijay, 2011-10-31
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9925948] D'Eustachio, Peter, 2024-10-28
[InstanceEdit:9926226] D'Eustachio, Peter, 2024-10-31
[InstanceEdit:9927661] D'Eustachio, Peter, 2024-11-08
nameHistidine is decarboxylated to histamine
H(+) + L-histidine => CO2 + histamine
output[SimpleEntity:175992] Hist [cytosol]
[SimpleEntity:113528] CO2 [cytosol]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2011-12-06
reviewed[InstanceEdit:1828027] D'Eustachio, P, 2011-10-26
[InstanceEdit:9927660] D'Eustachio, Peter, 2024-11-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016227] R-HSA-977301.3
structureModified[InstanceEdit:9925948] D'Eustachio, Peter, 2024-10-28
summation[Summation:977309] Decarboxylation of L-Histidine happens analogously to other ...
(hasEvent)[Pathway:70921] Histidine catabolism [Homo sapiens]
(precedingEvent)[Reaction:175993] HNMT transfers CH3 group from AdoMet to Hist [Homo sapiens]
(updatedInstance)[_UpdateTracker:9928452] Update Tracker - [Reaction:977301] Histidine is decarboxylated to histamine - v91:[removeInput]
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