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Details on Person Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation

Class:IdLiteratureReference:9770874
_displayNameSystematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation
_timestamp2022-04-15 15:08:14
author[Person:9770811] Li, Wencheng
[Person:9770869] You, Bei
[Person:9770815] Hoque, Mainul
[Person:9770858] Zheng, Dinghai
[Person:9770803] Luo, Wenting
[Person:9770831] Ji, Zhe
[Person:9770868] Park, Ji Yeon
[Person:9770880] Gunderson, Samuel I
[Person:9770862] Kalsotra, Auinash
[Person:4615842] Manley, James L
[Person:9770813] Tian, Bin
created[InstanceEdit:9770867] Orlic-Milacic, Marija, 2022-04-15
journalPLoS Genet
pagese1005166
pubMedIdentifier25906188
titleSystematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation
volume11
year2015
(literatureReference)[Summation:9968763] NUDT21 (CPSF5, also known as CFIm25), a Nudix hydrolase supe...
[Summation:9970148]

RNA polymerase II (RNA Pol II) slows around the polyA sig...
[Summation:9970515]

CPSF3 (also known as CPSF73) is the endonuclease that cle...
[Summation:9970516]

CPSF3 (also known as CPSF73) is the endonuclease that cle...
[Summation:9970517]

CPSF3 (also known as CPSF73) is the endonuclease that cle...
[Reaction:9770882] FIP1L1 binds proximal PAS in the last exon [Homo sapiens]
[Reaction:9770891] PABPN1 and PABPC1 promote usage of distal PASs [Homo sapiens]
[Reaction:9970193] CPSF3 cleaves pre-mRNA at distal 3'UTR PAS [Homo sapiens]
[Reaction:9970282] U1 snRNP suppresses CPSF3-mediated pre-mRNA cleavage at intronic PAS [Homo sapiens]
[Reaction:9970294] CPSF3 cleaves pre-mRNA at proximal 3'UTR PAS [Homo sapiens]

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