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Details on Person In mouse neurons, Srf (serum response factor) stimulates Npa...

Class:IdSummation:9769694
_displayNameIn mouse neurons, Srf (serum response factor) stimulates Npa...
_timestamp2022-03-21 20:39:13
created[InstanceEdit:9769695] Orlic-Milacic, Marija, 2022-03-21
literatureReference[LiteratureReference:9768824] Adult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression
[LiteratureReference:9768827] SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model
[LiteratureReference:9768823] Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injury
textIn mouse neurons, Srf (serum response factor) stimulates Npas4 gene transcription (Kuzniewska et al. 2016, Lösing et al. 2017, Förstner and Knöll 2019) by directly binding to evolutionarily conserved Srf binding sites in the promoter region of the Npas4 gene (Kuzniewska et al. 2016).
(summation)[BlackBoxEvent:9768820] Srf stimulates Npas4 gene transcription [Mus musculus]
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