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Details on Person UniProt:Q9BYG4 PARD6G
| Class:Id | ReferenceGeneProduct:97688 |
|---|---|
| _chainChangeLog | chain:1-376 added on Sat February 7 2015 |
| _displayName | UniProt:Q9BYG4 PARD6G |
| _timestamp | 2024-11-03 19:42:32 |
| chain | chain:1-376 |
| checksum | E5A4EF521403CA11 |
| comment | FUNCTION Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity).SUBUNIT Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, RHOQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.INTERACTION Widely expressed, with a higher expression in fetal and adult kidney.DOMAIN The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.SIMILARITY Belongs to the PAR6 family. |
| description | recommendedName: Partitioning defective 6 homolog gamma shortName: PAR-6 gamma alternativeName: PAR6D |
| geneName | PARD6G PAR6G |
| identifier | Q9BYG4 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cell cycle Cell division Cell junction Cell membrane Cytoplasm Membrane Proteomics identification Reference proteome Tight junction |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PARD6G |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8990301] ENSEMBL:ENSG00000178184 PARD6G [Homo sapiens] |
| secondaryIdentifier | PAR6G_HUMAN A8QM57 |
| sequenceLength | 376 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8970191] UniProt:Q9BYG4-1 PARD6G [Homo sapiens] [ReferenceIsoform:8970192] UniProt:Q9BYG4-2 PARD6G [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:418192] PARD6G [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:419967] PARD6G [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9BYG4 PARD6G (97688)
