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Details on Person miR-224 represses NPAS4 mRNA translation

Class:Id	BlackBoxEvent:9768782
_displayName	miR-224 represses NPAS4 mRNA translation
_doRelease	TRUE
_timestamp	2024-11-04 23:39:41
authored	[InstanceEdit:9770624] Orlic-Milacic, Marija, 2022-04-08
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9768789] Orlic-Milacic, Marija, 2022-03-14
edited	[InstanceEdit:9795246] Orlic-Milacic, Marija, 2022-08-02
input	[EntityWithAccessionedSequence:9769438] NPAS4 mRNA [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9768769] Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs
modified	[InstanceEdit:9768800] Orlic-Milacic, Marija, 2022-03-14 [InstanceEdit:9769464] Orlic-Milacic, Marija, 2022-03-16 [InstanceEdit:9773238] Orlic-Milacic, Marija, 2022-05-04 [InstanceEdit:9773770] Orlic-Milacic, Marija, 2022-05-09 [InstanceEdit:9795250] Orlic-Milacic, Marija, 2022-08-02 [InstanceEdit:9795251] Orlic-Milacic, Marija, 2022-08-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9927173] Orlic-Milacic, Marija, 2024-11-04
name	miR-224 represses NPAS4 mRNA translation
negativePrecedingEvent	[NegativePrecedingEvent:9927162] Negative relationship: Activated glucocorticoid receptor represses NPAS4 gene transcription [NegativePrecedingEvent:9927163] Negative relationship: NPAS4 gene transcription in non-neuronal cells is repressed by REST [NegativePrecedingEvent:9927165] Negative relationship: NPAS4 gene transcription is repressed by KCNIP3 [NegativePrecedingEvent:9927161] Incorrect Order: NPAS4 gene transcription is stimulated by NPAS4 [NegativePrecedingEvent:9927169] Incorrect Order: SRF stimulates NPAS4 gene transcription
output	[EntityWithAccessionedSequence:9769446] NPAS4 [cytosol] [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:9769450] Negative gene expression regulation by 'NPAS4 mRNA:miR-224-5p RISC [cytosol]'
releaseDate	2022-09-14
reviewed	[InstanceEdit:9795249] Lin, Yingxi, 2022-07-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9768792] R-HSA-9768782.3
summation	[Summation:9768799] miR-224 was shown to downregulate expression from the NPAS4 ...
(hasEvent)	[Pathway:9768778] Regulation of NPAS4 mRNA translation [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9927164] Negative relationship: miR-224 represses NPAS4 mRNA translation [NegativePrecedingEvent:9927166] Negative relationship: miR-224 represses NPAS4 mRNA translation
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No pathways have been reviewed or authored by miR-224 represses NPAS4 mRNA translation (9768782)