Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SNAI2 represses CDH1 gene transcription

Class:Id	BlackBoxEvent:9768484
_displayName	SNAI2 represses CDH1 gene transcription
_doRelease	TRUE
_timestamp	2025-05-23 13:36:29
authored	[InstanceEdit:9768370] Orlic-Milacic, Marija, 2022-03-11
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9768370] Orlic-Milacic, Marija, 2022-03-11
edited	[InstanceEdit:9930690] Orlic-Milacic, Marija, 2024-12-05
input	[EntityWithAccessionedSequence:9756422] CDH1 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimeric	FALSE
literatureReference	[LiteratureReference:9857452] Calreticulin represses E-cadherin gene expression in Madin-Darby canine kidney cells via Slug [LiteratureReference:9857455] SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma [LiteratureReference:9768562] The SLUG zinc-finger protein represses E-cadherin in breast cancer
modified	[InstanceEdit:9796542] Orlic-Milacic, Marija, 2022-08-10 [InstanceEdit:9796545] Orlic-Milacic, Marija, 2022-08-10 [InstanceEdit:9857461] Rothfels, Karen, 2024-01-04 [InstanceEdit:9930699] Orlic-Milacic, Marija, 2024-12-05 [InstanceEdit:9935648] Orlic-Milacic, Marija, 2025-01-17 [InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20 [InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
name	SNAI2 represses CDH1 gene transcription
output	[EntityWithAccessionedSequence:9793365] CDH1 mRNA [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9768533] SNAI2 binds CDH1 gene promoter [Homo sapiens] [BlackBoxEvent:9825406] SNAI2 gene expression [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:9796544] Negative gene expression regulation by 'SNAI2:CDH1 gene [nucleoplasm]'
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9768579] R-HSA-9768484.1
summation	[Summation:9796540] CDH1 expression is repressed by binding of SNAI2, also known...
(hasEvent)	[Pathway:9764725] Negative Regulation of CDH1 Gene Transcription [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9954048] Negative relationship: SNAI2 represses CDH1 gene transcription [NegativePrecedingEvent:9954055] Negative relationship: SNAI2 represses CDH1 gene transcription [NegativePrecedingEvent:9954061] Negative relationship: SNAI2 represses CDH1 gene transcription [NegativePrecedingEvent:9954098] Negative relationship: SNAI2 represses CDH1 gene transcription
[Change default viewing format]

No pathways have been reviewed or authored by SNAI2 represses CDH1 gene transcription (9768484)