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Details on Person FOXQ1 represses CDH1 gene transcription

Class:Id	BlackBoxEvent:9768079
_displayName	FOXQ1 represses CDH1 gene transcription
_doRelease	TRUE
_timestamp	2025-05-23 13:34:20
authored	[InstanceEdit:9768077] Orlic-Milacic, Marija, 2022-03-03
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9768077] Orlic-Milacic, Marija, 2022-03-03
edited	[InstanceEdit:9931153] Orlic-Milacic, Marija, 2024-12-10
input	[EntityWithAccessionedSequence:9756422] CDH1 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimeric	FALSE
literatureReference	[LiteratureReference:9768078] Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis [LiteratureReference:9931147] FOXQ1 promotes esophageal cancer proliferation and metastasis by negatively modulating CDH1
modified	[InstanceEdit:9931153] Orlic-Milacic, Marija, 2024-12-10 [InstanceEdit:9931759] Orlic-Milacic, Marija, 2024-12-12 [InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20 [InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
name	FOXQ1 represses CDH1 gene transcription
output	[EntityWithAccessionedSequence:9793365] CDH1 mRNA [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9768082] FOXQ1 bind CDH1 gene promoter [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:9931150] Negative gene expression regulation by 'FOXQ1:CDH1 gene [nucleoplasm]'
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9768084] R-HSA-9768079.1
structureModified	[InstanceEdit:9931153] Orlic-Milacic, Marija, 2024-12-10
summation	[Summation:9931140] FOXQ1 directly represses transcription of the CDH1 gene (Zha...
(hasEvent)	[Pathway:9764725] Negative Regulation of CDH1 Gene Transcription [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9768614] miR-9 inhibits CDH1 mRNA translation [Homo sapiens] [Reaction:9768616] miR-9 binds CDH1 mRNA [Homo sapiens] [BlackBoxEvent:9768618] miR-10b inhibits CDH1 mRNA translation [Homo sapiens] [Reaction:9768643] miR-10b binds CDH1 mRNA [Homo sapiens]
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No pathways have been reviewed or authored by FOXQ1 represses CDH1 gene transcription (9768079)