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Details on Person Factor I inactivates plasma Factor H-bound C3b

Class:Id	Reaction:976743
_displayName	Factor I inactivates plasma Factor H-bound C3b
_doRelease	TRUE
_timestamp	2012-03-01 11:21:25
authored	[InstanceEdit:981647] Jupe, S, 2010-10-26
catalystActivity	[CatalystActivity:977368] serine-type endopeptidase activity of CFI:CFH:C3b [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:976791] Jupe, S, 2010-10-13
edited	[InstanceEdit:983442] Jupe, S, 2010-11-01
input	[Complex:976770] CFI:CFH:C3b [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:976744] Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I
modified	[InstanceEdit:977377] Jupe, S, 2010-10-18 [InstanceEdit:977612] Jupe, S, 2010-10-20 [InstanceEdit:981705] Jupe, S, 2010-10-26 [InstanceEdit:998152] Jupe, S, 2010-11-09 [InstanceEdit:1096479] Jupe, S, 2010-11-30 [InstanceEdit:1168688] Jupe, S, 2011-01-06 [InstanceEdit:2109565] Jupe, S, 2012-02-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Factor I inactivates plasma Factor H-bound C3b
output	[Complex:976749] CFI [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:976788] CFH [extracellular region] [Homo sapiens] [Complex:976805] iC3b [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:976779] C3f [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:976810] Complement factor I binds to extracellular Factor H:C3b [Homo sapiens] [Reaction:976768] Factor H binds to C3b [Homo sapiens] [Reaction:976801] Complement factor I complex formation [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2109568] Bradley, DT, 2012-02-13 [InstanceEdit:2109566] Fraczek, LA, 2012-02-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158080] R-HSA-976743.2
summation	[Summation:976792] Complement factor I (CFI) cleaves the alpha chain of C3b at ...
(hasEvent)	[Pathway:977606] Regulation of Complement cascade [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783540] Update Tracker - [Reaction:976743] Factor I inactivates plasma Factor H-bound C3b - v56:[modifyText]
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No pathways have been reviewed or authored by Factor I inactivates plasma Factor H-bound C3b (976743)