Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Negative regulation by 'SUCCA: PHD2,3:LIMD1, AJUBA, WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]' Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
| Class:Id | RegulationReference:9767140 |
|---|---|
| _displayName | Negative regulation by 'SUCCA: PHD2,3:LIMD1, AJUBA, WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]' Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase |
| _timestamp | 2022-02-24 22:03:56 |
| created | [InstanceEdit:9767141] Rothfels, Karen, 2022-02-24 |
| literatureReference | [LiteratureReference:9763328] Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase [LiteratureReference:9763394] Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations [LiteratureReference:9763362] Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF |
| regulation | [NegativeRegulation:9767139] Negative regulation by 'SUCCA: PHD2,3:LIMD1, AJUBA, WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]' |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Negative regulation by 'SUCCA: PHD2,3:LIMD1, AJUBA, WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]' Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase (9767140)
