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Details on Person KEAP1 is ubiquitinated by the CUL3:RBX1 complex in an SQSTM1...

Class:IdSummation:9766643
_displayNameKEAP1 is ubiquitinated by the CUL3:RBX1 complex in an SQSTM1...
_timestamp2022-02-23 18:51:23
created[InstanceEdit:9766650] Rothfels, Karen, 2022-02-23
textKEAP1 is ubiquitinated by the CUL3:RBX1 complex in an SQSTM1-dependent manner (Zhang et al, 2005). Ubiquitination of KEAP1 renders it a substrate for SQSTM1-dependent degradation through the selective autophagy pathway (Zhang et al, 2005; Taguchi et al, 2012).
(summation)[Reaction:9766645] CUL3:RBX1 ubiquitinates KEAP1 [Homo sapiens]
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