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Details on Person Expression of Osr1 in intermediate mesoderm

Class:IdBlackBoxEvent:9766551
_displayNameExpression of Osr1 in intermediate mesoderm
_doReleaseTRUE
_timestamp2023-05-09 02:41:55
authored[InstanceEdit:9766557] May, Bruce, 2022-02-22
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9766555] May, Bruce, 2022-02-22
edited[InstanceEdit:9766557] May, Bruce, 2022-02-22
input[EntityWithAccessionedSequence:9761169] Osr1 gene [nucleoplasm] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9766553] Cloning and expression analysis of a mouse gene related to Drosophila odd-skipped
[LiteratureReference:9766554] The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 function
[LiteratureReference:9792535] Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells
[LiteratureReference:9792612] Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney
[LiteratureReference:9774485] Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development
[LiteratureReference:9774508] Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms
[LiteratureReference:9774593] Induction of intermediate mesoderm by retinoic acid receptor signaling from differentiating mouse embryonic stem cells
[LiteratureReference:9774587] Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells
[LiteratureReference:9792550] The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate
modified[InstanceEdit:9766561] May, Bruce, 2022-02-22
[InstanceEdit:9774530] May, Bruce, 2022-05-24
[InstanceEdit:9774622] May, Bruce, 2022-05-25
[InstanceEdit:9792557] May, Bruce, 2022-05-26
[InstanceEdit:9792616] May, Bruce, 2022-05-28
[InstanceEdit:9792617] May, Bruce, 2022-05-28
[InstanceEdit:9833802] May, Bruce, 2023-05-03
[InstanceEdit:9834661] May, Bruce, 2023-05-09
[InstanceEdit:9835794] Matthews, Lisa, 2023-05-17
nameExpression of Osr1 in intermediate mesoderm
output[EntityWithAccessionedSequence:9761196] Osr1 [nucleoplasm] [Mus musculus]
regulatedBy[PositiveGeneExpressionRegulation:9774510] Positive gene expression regulation by 'Pax2 [nucleoplasm]'
[PositiveGeneExpressionRegulation:9774481] Positive gene expression regulation by 'atRA [extracellular region]'
[NegativeGeneExpressionRegulation:9792540] Negative gene expression regulation by 'Foxc1 [nucleoplasm]'
[NegativeGeneExpressionRegulation:9792549] Negative gene expression regulation by 'Foxc2 [nucleoplasm]'
regulationReference[RegulationReference:9774524] Positive gene expression regulation by 'Pax2 [nucleoplasm]' Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms
[RegulationReference:9774604] Positive gene expression regulation by 'atRA [extracellular region]' Induction of intermediate mesoderm by retinoic acid receptor signaling from differentiating mouse embryonic stem cells
[RegulationReference:9792548] Negative gene expression regulation by 'Foxc1 [nucleoplasm]' The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate
[RegulationReference:9792552] Negative gene expression regulation by 'Foxc2 [nucleoplasm]' The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate
releaseDate2023-06-07
reviewed[InstanceEdit:9833800] Tam, Patrick P L, 2023-05-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9766559] R-MMU-9766551.1
summation[Summation:9774616] Odd-skipped related 1 (Osr1, also called Odd1) is expressed ...
(inferredFrom)[BlackBoxEvent:9761186] Expression of OSR1 in intermediate mesoderm [Homo sapiens]
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