Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person SQSTM1 oligomer is phosphorylated

Class:IdReaction:9766532
_displayNameSQSTM1 oligomer is phosphorylated
_doReleaseTRUE
_timestamp2022-02-28 16:33:42
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
catalystActivity[CatalystActivity:5250906] protein serine/threonine kinase activity of unknown kinase [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9766533] Rothfels, Karen, 2022-02-22
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
inferredFrom
input[Complex:9759097] SQSTM1 oligomer [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9766496] Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy
[LiteratureReference:9759058] p62 links autophagy and Nrf2 signaling
[LiteratureReference:9759008] Regulation of selective autophagy: the p62/SQSTM1 paradigm
[LiteratureReference:9708494] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
modified[InstanceEdit:9766580] Rothfels, Karen, 2022-02-22
[InstanceEdit:9767052] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSQSTM1 oligomer is phosphorylated
output[Complex:9766527] p-S349 SQSTM1 oligomer [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9766534] R-HSA-9766532.2
summation[Summation:9766520] SQSTM1 is phosphorylated at serine 349 by an unknown kinase ...
(hasEvent)[Pathway:9755511] KEAP1-NFE2L2 pathway [Homo sapiens]
(precedingEvent)[Reaction:9759169] p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by SQSTM1 oligomer is phosphorylated (9766532)