Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Negative regulation by 'MMP5:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]' Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein

Class:IdRegulationReference:9766201
_displayNameNegative regulation by 'MMP5:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]' Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein
_timestamp2022-02-18 00:58:36
created[InstanceEdit:9766200] Shamovsky, Veronica, 2022-02-18
literatureReference[LiteratureReference:9704980] Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein
[LiteratureReference:9704978] Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis
[LiteratureReference:9754606] Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain
regulation[NegativeRegulation:9766196] Negative regulation by 'MMP5:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]'
(regulationReference)[Reaction:420661] Crumbs forms a ternary complex with Pals1 and PATJ at tight junctions [Homo sapiens]
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No pathways have been reviewed or authored by Negative regulation by 'MMP5:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]' Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein (9766201)
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