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Details on Person PKM and TGIF2 repress CDH1 gene transcription

Class:Id	BlackBoxEvent:9766065
_displayName	PKM and TGIF2 repress CDH1 gene transcription
_doRelease	TRUE
_timestamp	2025-05-23 13:35:26
authored	[InstanceEdit:9766059] Orlic-Milacic, Marija, 2022-02-17
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9766059] Orlic-Milacic, Marija, 2022-02-17
edited	[InstanceEdit:9931493] Orlic-Milacic, Marija, 2024-12-12
input	[EntityWithAccessionedSequence:9756422] CDH1 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimeric	FALSE
literatureReference	[LiteratureReference:9766058] Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition [LiteratureReference:9931497] PPP1R26 drives hepatocellular carcinoma progression by controlling glycolysis and epithelial-mesenchymal transition
modified	[InstanceEdit:9931506] Orlic-Milacic, Marija, 2024-12-12 [InstanceEdit:9931759] Orlic-Milacic, Marija, 2024-12-12 [InstanceEdit:9935648] Orlic-Milacic, Marija, 2025-01-17 [InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20 [InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
name	PKM and TGIF2 repress CDH1 gene transcription
output	[EntityWithAccessionedSequence:9793365] CDH1 mRNA [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9766062] PKM and TGIF2 bind CDH1 gene promoter [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:9931496] Negative gene expression regulation by 'PKM:TGIF2:CDH1 gene [nucleoplasm]'
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9766072] R-HSA-9766065.1
structureModified	[InstanceEdit:9931506] Orlic-Milacic, Marija, 2024-12-12
summation	[Summation:9931492] Pyruvate kinase PKM (also known as PKM2) and TGF-beta-induce...
(hasEvent)	[Pathway:9764725] Negative Regulation of CDH1 Gene Transcription [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9954072] Negative relationship: PKM and TGIF2 repress CDH1 gene transcription [NegativePrecedingEvent:9954076] Negative relationship: PKM and TGIF2 repress CDH1 gene transcription [NegativePrecedingEvent:9954089] Negative relationship: PKM and TGIF2 repress CDH1 gene transcription [NegativePrecedingEvent:9954112] Negative relationship: PKM and TGIF2 repress CDH1 gene transcription
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No pathways have been reviewed or authored by PKM and TGIF2 repress CDH1 gene transcription (9766065)