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Details on Person MCRIP1 binds CTBP1

Class:IdReaction:9765974
_displayNameMCRIP1 binds CTBP1
_doReleaseTRUE
_timestamp2025-05-23 13:34:47
authored[InstanceEdit:9765972] Orlic-Milacic, Marija, 2022-02-17
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9765972] Orlic-Milacic, Marija, 2022-02-17
edited[InstanceEdit:9930966] Orlic-Milacic, Marija, 2024-12-07
input[EntityWithAccessionedSequence:9765961] MCRIP1 [nucleoplasm] [Homo sapiens]
[Complex:9930955] CTBP1 homodimer [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9936137] Rothfels, Karen, 2025-01-20
isChimericFALSE
literatureReference[LiteratureReference:9765962] MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP
modified[InstanceEdit:9815992] Orlic-Milacic, Marija, 2022-08-31
[InstanceEdit:9930958] Orlic-Milacic, Marija, 2024-12-07
[InstanceEdit:9930967] Orlic-Milacic, Marija, 2024-12-07
[InstanceEdit:9936139] Orlic-Milacic, Marija, 2025-01-20
[InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
nameMCRIP1 binds CTBP1
output[Complex:9765971] MCRIP1:CTBP1 [nucleoplasm] [Homo sapiens]
regulatedBy[NegativeRegulation:9765965] Negative regulation by 'p-T,Y MAPK monomers and dimers [nucleoplasm]'
releaseDate2025-06-18
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9765977] R-HSA-9765974.1
structureModified[InstanceEdit:9930958] Orlic-Milacic, Marija, 2024-12-07
summation[Summation:9815988] MCRIP1 forms a complex with CTBP1. Binding of MCRIP1 to CTBP...
(hasEvent)[Pathway:9764725] Negative Regulation of CDH1 Gene Transcription [Homo sapiens]
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