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Details on Person MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP

Class:IdLiteratureReference:9765962
_displayNameMCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP
_timestamp2022-02-17 17:31:46
author[Person:9653737] Ichikawa, Kenji
[Person:9765964] Kubota, Yuji
[Person:9765968] Nakamura, Takanori
[Person:9765970] Weng, Jane S
[Person:9765967] Tomida, Taichiro
[Person:3228468] Saito, Haruo
[Person:3228466] Takekawa, Mutsuhiro
created[InstanceEdit:9765972] Orlic-Milacic, Marija, 2022-02-17
journalMol Cell
pages35-46
pubMedIdentifier25728771
titleMCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP
volume58
year2015
(literatureReference)[Summation:9815988] MCRIP1 forms a complex with CTBP1. Binding of MCRIP1 to CTBP...
[Summation:9815993] Activated MAPKs (ERKs) phosphorylate MCRIP1 on conserved res...
[Summation:9816020] CTBP1 (Cowger et al. 2007, Bruton et al. 2008; Deng et al. 2...
[Reaction:9765960] ERKs phosphorylate MCRIP1 [Homo sapiens]
[Reaction:9765973] CTBP1,CTBP2 binds ZEB1 [Homo sapiens]
[Reaction:9765974] MCRIP1 binds CTBP1 [Homo sapiens]
[Reaction:9768477] CTBP1,CTBP2 binds CDH1 gene promoter [Homo sapiens]
[RegulationReference:9765966] Positive regulation by 'CTBP1:ZEB1 [nucleoplasm]' MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP
[Complex:9765959] CTBP1,CTBP2:ZEB1 [nucleoplasm] [Homo sapiens]
[Complex:9765971] MCRIP1:CTBP1 [nucleoplasm] [Homo sapiens]
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