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Details on Person MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition

Class:IdLiteratureReference:9765848
_displayNameMPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition
_timestamp2022-02-16 18:11:49
author[Person:9625306] Sun, Lidong
[Person:9765847] Kokura, Kenji
[Person:9765849] Izumi, Victoria
[Person:9765851] Koomen, John M
[Person:3214823] Seto, Edward
[Person:5096487] Chen, Jiandong
[Person:3214870] Fang, Jia
created[InstanceEdit:9765853] Orlic-Milacic, Marija, 2022-02-16
journalEMBO Rep
pages689-99
pubMedIdentifier25870236
titleMPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition
volume16
year2015
(literatureReference)[Pathway:9764560] Regulation of CDH1 Gene Transcription [Homo sapiens]
[Pathway:9764725] Negative Regulation of CDH1 Gene Transcription [Homo sapiens]
[BlackBoxEvent:9764778] ZEB1 represses CDH1 gene transcription [Homo sapiens]
[Reaction:9765850] ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter [Homo sapiens]
[BlackBoxEvent:9765852] MPHOSPH8 (MPP8) represses CDH1 gene transcription [Homo sapiens]
[Summation:9815397]

Direct repression of CDH1 gene transcription was first de...
[Summation:9931122] MPHOSPH8 (also known as M-phase phosphoprotein 8 or MPP8) bi...

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