Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person D'Eustachio, Peter, 2022-02-14

Class:IdInstanceEdit:9764875
_displayNameD'Eustachio, Peter, 2022-02-14
_timestamp2022-02-14 15:46:48
author[Person:140934] D'Eustachio, Peter
dateTime2022-02-14 15:46:42
(created)[NegativePrecedingEvent:9764871] Futile Cycle: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin
[NegativePrecedingEvent:9764872] Futile Cycle: CD320-mediated TCN2:RCbl uptake and delivery to lysosome
[NegativePrecedingEvent:9764873] Different Cell Type: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells)
[NegativePrecedingEvent:9764874] Incorrect Order: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR
[NegativePrecedingEvent:9764876] Incorrect Order: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR
[NegativePrecedingEvent:9764877] Incorrect Order: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR
[NegativePrecedingEvent:9764878] Different Cell Type: Pancreatic proteases degrade TCN1:RCbl
[NegativePrecedingEvent:9764879] Incorrect Order: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria
[NegativePrecedingEvent:9764880] Futile Cycle: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome
[NegativePrecedingEvent:9764881] Different Cell Type: TCN2 binds RCbl in the circulation
List all 16 refering instances
(modified)[Reaction:174374] MTR transfers CH3 from MeCbl to HCYS [Homo sapiens]
[PathwayDiagram:532187] Diagram of Metabolism of water-soluble vitamins and cofactors, Defective AMN causes MGA1, Defective CD320 causes MMATC, Defective CUBN causes MGA1, Defective CBLIF causes IFD, Defective MMAA causes MMA, cblA type, Defective MMAB causes MMA, cblB type, Defective MMACHC causes MAHCC, Defective MMADHC causes MMAHCD, Defective MTR causes HMAG, Defective MTRR causes HMAE, Defective TCN2 causes TCN2 deficiency, Defective HLCS causes multiple carboxylase deficiency, Defective BTD causes biotidinase deficiency, and Defective ABCD4 causes MAHCJ
[Reaction:3000074] TCN2 binds RCbl in the circulation [Homo sapiens]
[Reaction:3000103] CUBN:AMN binds CBLIF:RCbl [Homo sapiens]
[Reaction:3000120] CBLIF binds RCbl [Homo sapiens]
[Reaction:3000122] CD320 binds extracellular TCN2:RCbl [Homo sapiens]
[BlackBoxEvent:3000263] TCN2:RCbl is degraded to release RCbl [Homo sapiens]
[Reaction:3095889] MMACHC dealkylates RCbl [Homo sapiens]
[Reaction:3095901] ABCC1 transports cytosolic RCbl to extracellular region [Homo sapiens]
[Reaction:3149494] MMACHC:cob(II)alamin binds MMADHC [Homo sapiens]
List all 13 refering instances
[Change default viewing format]
No pathways have been reviewed or authored by D'Eustachio, Peter, 2022-02-14 (9764875)
Follow Reactome