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Query author contributions in Reactome

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Details on Person Orlic-Milacic, Marija, 2022-02-02

Class:IdInstanceEdit:9763429
_displayNameOrlic-Milacic, Marija, 2022-02-02
_timestamp2022-02-02 18:14:28
author[Person:1169272] Orlic-Milacic, Marija
dateTime2022-02-02 18:13:40
(modified)[PathwayDiagram:5685945] Diagram of HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), Defective homologous recombination repair (HRR) due to BRCA1 loss-of-function, Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function, Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function, Impaired BRCA2 binding to SEM1 (DSS1), Impaired BRCA2 binding to RAD51, Impaired BRCA2 binding to PALB2, and Impaired BRCA2 translocation to the nucleus
[Complex:9709608] SEM1:BRCA2 mutants (PALB2 binding):p-T309-RAD51 complex [nucleoplasm] [Homo sapiens]
[Complex:9709609] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1 [nucleoplasm] [Homo sapiens]
[Complex:9709610] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1:BCDX2 complex [nucleoplasm] [Homo sapiens]
[EntityFunctionalStatus:9709612] loss_of_function and partial_loss_of_function of 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1:BCDX2 complex [nucleoplasm]
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2022-02-02 (9763429)
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