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Details on Person MYC binds the NFE2L2 promoter

Class:IdReaction:9762097
_displayNameMYC binds the NFE2L2 promoter
_doReleaseTRUE
_timestamp2022-02-28 16:32:38
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9762099] Rothfels, Karen, 2022-01-17
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
input[EntityWithAccessionedSequence:9762042] NFE2L2 gene [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:188379] MYC [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9761694] c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
[LiteratureReference:9761957] NRF2, a Transcription Factor for Stress Response and Beyond
[LiteratureReference:9761951] NRF2 addiction in cancer cells
modified[InstanceEdit:9767020] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMYC binds the NFE2L2 promoter
output[Complex:9762083] NFE2L2 gene:MYC [nucleoplasm] [Homo sapiens]
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9762108] R-HSA-9762097.2
summation[Summation:9762070] MYC binds to its cognate binding site in the promoter of the...
(hasEvent)[Pathway:9818749] Regulation of NFE2L2 gene expression [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9762100] MYC- and NICD1-dependent NFE2L2 gene expression [Homo sapiens]
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No pathways have been reviewed or authored by MYC binds the NFE2L2 promoter (9762097)