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Details on Person p14ARF binds NFE2L2:CREBBP, EP300

Class:IdReaction:9761836
_displayNamep14ARF binds NFE2L2:CREBBP, EP300
_doReleaseTRUE
_timestamp2022-02-28 16:34:02
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9761837] Rothfels, Karen, 2022-01-15
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
input[EntityWithAccessionedSequence:1629813] p14ARF [nucleoplasm] [Homo sapiens]
[Complex:9760065] p-NFE2L2:CREBBP,EP300 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9761593] NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression
[LiteratureReference:9759989] Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
[LiteratureReference:9708514] Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
[LiteratureReference:9708494] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
[LiteratureReference:9761634] Oxidative Damage and Antioxidant Defense in Ferroptosis
[LiteratureReference:9761641] Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators
modified[InstanceEdit:9767067] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namep14ARF binds NFE2L2:CREBBP, EP300
output[Complex:9761732] p-NFE2L2:CREBBP,EP300;p14ARF [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9761838] R-HSA-9761836.2
summation[Summation:9761801] p14ARF binds to NFE2L2 and inhibits its CREBBP/EP300-depende...
(hasEvent)[Pathway:9759194] Nuclear events mediated by NFE2L2 [Homo sapiens]
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No pathways have been reviewed or authored by p14ARF binds NFE2L2:CREBBP, EP300 (9761836)