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Details on Person NFE2L2 binds the TKT gene

Class:IdReaction:9761834
_displayNameNFE2L2 binds the TKT gene
_doReleaseTRUE
_timestamp2022-02-28 16:33:08
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9761833] Rothfels, Karen, 2022-01-15
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
input[EntityWithAccessionedSequence:8957459] TKT gene [nucleoplasm] [Homo sapiens]
[CandidateSet:9708562] p-NFE2L2 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9761654] The Role of the Pentose Phosphate Pathway in Diabetes and Cancer
[LiteratureReference:9708494] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
[LiteratureReference:9761633] Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism
[LiteratureReference:9759995] Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
[LiteratureReference:9759273] Beneficial role of Nrf2 in regulating NADPH generation and consumption
[LiteratureReference:9761603] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
[LiteratureReference:9761694] c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
modified[InstanceEdit:9767035] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNFE2L2 binds the TKT gene
output[Complex:9761735] TKT gene:p-NFE2L2 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9761835] R-HSA-9761834.2
summation[Summation:9761797] The TKT gene encodes transketolase, an enzyme that catalyzes...
(hasEvent)[Pathway:9818028] NFE2L2 regulates pentose phosphate pathway genes [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9761852] NFE2L2-dependent TKT gene expression [Homo sapiens]
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No pathways have been reviewed or authored by NFE2L2 binds the TKT gene (9761834)