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Details on Person NFE2L2 binds the IDH1 gene

Class:IdReaction:9761822
_displayNameNFE2L2 binds the IDH1 gene
_doReleaseTRUE
_timestamp2022-02-28 16:32:56
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9761821] Rothfels, Karen, 2022-01-15
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
input[EntityWithAccessionedSequence:8958018] IDH1 gene [nucleoplasm] [Homo sapiens]
[CandidateSet:9708562] p-NFE2L2 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9761580] IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives
[LiteratureReference:9761658] The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism
[LiteratureReference:9761603] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
[LiteratureReference:9759995] Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
[LiteratureReference:9759273] Beneficial role of Nrf2 in regulating NADPH generation and consumption
[LiteratureReference:9708494] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
[LiteratureReference:9761640] Oxidative Stress in Cancer
modified[InstanceEdit:9767029] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNFE2L2 binds the IDH1 gene
output[Complex:9761757] IDH1 gene:p-NFE2L2 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9761823] R-HSA-9761822.2
summation[Summation:9761773] IDH1 encodes the cytosolic NADP-dependent isocitrate dehydro...
(hasEvent)[Pathway:9818025] NFE2L2 regulating TCA cycle genes [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9761844] NFE2L2-dependent IDH1 gene expression [Homo sapiens]
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