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Details on Person c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
| Class:Id | LiteratureReference:9761694 |
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| _displayName | c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
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| _timestamp | 2022-01-15 22:48:17 |
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| author | [Person:9761684] Tang, Ya-Chu
[Person:9761686] Hsiao, Jenn-Ren
[Person:9761685] Jiang, Shih-Sheng
[Person:2399824] Chang, Jang-Yang
[Person:5623753] Chu, Pei-Yi
[Person:9761690] Liu, Ko-Jiunn
[Person:9761687] Fang, Hsun-Lang
[Person:9761696] Lin, Li-Mei
[Person:9761697] Chen, Huang-Hui
[Person:9761688] Huang, Yen-Wen
[Person:9761691] Chen, Yu-Tsen
[Person:9761692] Tsai, Fang-Yu
[Person:8852968] Lin, Su-Fang
[Person:9761695] Chuang, Yung-Jen
[Person:9761693] Kuo, Ching-Chuan |
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| created | [InstanceEdit:9761689] Rothfels, Karen, 2022-01-15 |
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| journal | Theranostics |
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| pages | 5232-5247 |
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| pubMedIdentifier | 33859744 |
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| title | c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
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| volume | 11 |
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| year | 2021 |
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| (literatureReference) | [BlackBoxEvent:8932309] NFE2L2 translocates from cytosol to nucleoplasm [Homo sapiens]
[Reaction:9761812] AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD [Homo sapiens]
[Reaction:9761834] NFE2L2 binds the TKT gene [Homo sapiens]
[BlackBoxEvent:9761852] NFE2L2-dependent TKT gene expression [Homo sapiens]
[Reaction:9762097] MYC binds the NFE2L2 promoter [Homo sapiens]
[BlackBoxEvent:9762100] MYC- and NICD1-dependent NFE2L2 gene expression [Homo sapiens]
[Complex:9761735] TKT gene:p-NFE2L2 [nucleoplasm] [Homo sapiens]
[RegulationReference:9761861] Positive gene expression regulation by 'TKT gene:p-NFE2L2 [nucleoplasm]' c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
[RegulationReference:9762101] Positive gene expression regulation by 'NFE2L2 gene:MYC [nucleoplasm]' c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
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