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Details on Person GspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space

Class:IdReaction:9760705
_displayNameGspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space
_doReleaseTRUE
_timestamp2025-05-21 07:42:25
authored[InstanceEdit:9760662] Stephan, Ralf, 2021-12-21
catalystActivity[CatalystActivity:9760693] transmembrane protein transporter activity of GspD2:GspC2:GspS2 [periplasmic space]
compartment[Compartment:1222638] periplasmic space
[Compartment:20798] cell outer membrane
[Compartment:984] extracellular region
created[InstanceEdit:9760696] Stephan, Ralf, 2021-12-22
disease[Disease:3134792] bacterial infectious disease
edited[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input[Complex:9760660] LT [periplasmic space] [Escherichia coli]
internalReviewed[InstanceEdit:9915005] Gillespie, Marc E, 2024-07-02
[InstanceEdit:9917579] Gillespie, Marc E, 2024-08-08
isChimericFALSE
literatureReference[LiteratureReference:9760687] YghG (GspSĪ²) is a novel pilot protein required for localization of the GspSĪ² type II secretion system secretin of enterotoxigenic Escherichia coli
[LiteratureReference:9760691] Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of Escherichia coli
[LiteratureReference:9760698] The binding of cholera toxin to the periplasmic vestibule of the type II secretion channel
[LiteratureReference:9760717] Type II secretion system: a magic beanstalk or a protein escalator
[LiteratureReference:9760176] Specificity of the type II secretion systems of enterotoxigenic Escherichia coli and Vibrio cholerae for heat-labile enterotoxin and cholera toxin
[LiteratureReference:9760694] Bacterial surface association of heat-labile enterotoxin through lipopolysaccharide after secretion via the general secretory pathway
[LiteratureReference:9760830] Electron Acceptors Induce Secretion of Enterotoxigenic Escherichia coli Heat-Labile Enterotoxin under Anaerobic Conditions through Promotion of GspD Assembly
[LiteratureReference:9760831] Structural insight into the assembly of the type II secretion system pilotin-secretin complex from enterotoxigenic Escherichia coli
modified[InstanceEdit:9760833] Stephan, Ralf, 2022-01-04
[InstanceEdit:9768331] Matthews, Lisa, 2022-03-05
[InstanceEdit:9912369] Stephan, Ralf, 2024-06-08
[InstanceEdit:9914259] Stephan, Ralf, 2024-06-23
[InstanceEdit:9915006] Stephan, Ralf, 2024-07-02
[InstanceEdit:9915160] Stephan, Ralf, 2024-07-03
[InstanceEdit:9917580] Stephan, Ralf, 2024-08-08
[InstanceEdit:9931098] Stephan, Ralf, 2024-12-10
[InstanceEdit:9933047] Stephan, Ralf, 2024-12-23
[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
nameGspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space
output[Complex:9760706] LT [extracellular region] [Escherichia coli]
precedingEvent
relatedSpecies[Species:9760713] Escherichia coli O78:H11
releaseDate2025-06-18
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9768336] R-HSA-9760705.1
summation[Summation:9760832] E. coli heat-labile enterotoxin (LT) is secreted from the pe...
(hasEvent)[Pathway:9760173] Secretion of toxins [Homo sapiens]
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No pathways have been reviewed or authored by GspD2:GspC2:GspS2 transports LT from periplasmic to extracellular space (9760705)
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