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Details on Person Addition of GlcNAc to position 5 by MGAT5

Class:Id	Reaction:975916
_displayName	Addition of GlcNAc to position 5 by MGAT5
_doRelease	TRUE
_timestamp	2010-12-02 14:40:11
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:975917] alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity of MGAT5 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:975912] Jassal, B, 2010-10-08
edited	[InstanceEdit:975912] Jassal, B, 2010-10-08
input	[SimpleEntity:975910] NGP [Golgi lumen] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:1015755] Characterization of UDP-N-acetylglucosamine:alpha-6-d-mannoside beta-1,6-N-acetylglucosaminyltransferase V from a human hepatoma cell line Hep3B [LiteratureReference:1015771] Increase in beta1-6 GlcNAc branching caused by N-acetylglucosaminyltransferase V directs integrin beta1 stability in human hepatocellular carcinoma cell line SMMC-7721 [LiteratureReference:1015767] Suppression of tumor growth and metastasis in Mgat5-deficient mice [LiteratureReference:1015761] The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin [LiteratureReference:1015738] MGAT5 alters the severity of multiple sclerosis [LiteratureReference:1015712] The implication of N-acetylglucosaminyltransferase V expression in gastric cancer
modified	[InstanceEdit:981614] Jassal, B, 2010-10-26 [InstanceEdit:1008193] Jassal, B, 2010-11-10 [InstanceEdit:1015777] Jassal, B, 2010-11-15 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1028800] Jassal, B, 2010-11-18 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of GlcNAc to position 5 by MGAT5
output	[OtherEntity:981617] Glycoprotein with GlcNAc in position 5 [Golgi lumen]
releaseDate	2010-12-14
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105608] R-HSA-975916.2
summation	[Summation:1015751] N-acetylglucosaminyltransferase (GnT)-V catalyzes the additi...
(hasEvent)	[Pathway:975577] N-Glycan antennae elongation [Homo sapiens]
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No pathways have been reviewed or authored by Addition of GlcNAc to position 5 by MGAT5 (975916)