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Details on Person NFE2L2 binds the PRDX1 promoter

Class:IdReaction:9759129
_displayNameNFE2L2 binds the PRDX1 promoter
_doReleaseTRUE
_timestamp2022-02-28 16:33:02
authored[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9759130] Rothfels, Karen, 2021-11-29
edited[InstanceEdit:9755506] Rothfels, Karen, 2021-10-08
input[EntityWithAccessionedSequence:8958034] PRDX1 gene [nucleoplasm] [Homo sapiens]
[CandidateSet:9708562] p-NFE2L2 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9708514] Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
[LiteratureReference:9758989] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
[LiteratureReference:9758974] Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology
[LiteratureReference:9708494] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
[LiteratureReference:9758994] Peroxiredoxin 1 - an antioxidant enzyme in cancer
[LiteratureReference:9759046] The role of peroxiredoxin 1 in redox sensing and transducing
modified[InstanceEdit:9767032] Rothfels, Karen, 2022-02-24
[InstanceEdit:9767541] Rothfels, Karen, 2022-02-28
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNFE2L2 binds the PRDX1 promoter
output[Complex:9759106] PRDX1 gene:p-NFE2L2 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2022-03-23
reviewed[InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9759132] R-HSA-9759129.2
summation[Summation:9759131] NFE2L2 binds to its consensus sequence in the promoter of th...
(hasEvent)[Pathway:9818027] NFE2L2 regulating anti-oxidant/detoxification enzymes [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9759189] NFE2L2-dependent PRDX1 gene expression [Homo sapiens]
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